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Chemical Structure : D77
CAS No.: 497836-10-9
Catalog No.: PC-45509Not For Human Use, Lab Use Only.
A potent inhibitor of HIV-1 integrase-LEDGF/p75 interaction.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $400 | In stock | |
| 50 mg | $1200 | In stock | |
| 100 mg | $1680 | In stock |
Bulk size, bulk discount!
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A potent inhibitor of HIV-1 integrase-LEDGF/p75 interaction; binds to IN and IN(T125A) with Kd of 5.81 and 15.2 uM; affects the HIV-1 IN nuclear distribution thus exhibiting antiretroviral activity.
HIV Infection
Preclinical
| M.Wt | 596.4458 | |
| Formula | C28H22BrNO7S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Benzoic acid, 4-[[5-bromo-4-[[2,4-dioxo-3-(2-oxo-2-phenylethyl)-5-thiazolidinylidene]methyl]-2-ethoxyphenoxy]methyl]- |
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1. Du L, et al. Biochem Biophys Res Commun. 2008 Oct 10;375(1):139-44.
2. Li P, et al. J Biomol Struct Dyn. 2011 Oct;29(2):311-23.
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