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Chemical Structure : D77
Catalog No.: PC-45509Not For Human Use, Lab Use Only.
D77 is a potent inhibitor of HIV-1 integrase-LEDGF/p75 interaction binds to IN and IN(T125A) with Kd of 5.81 and 15.2 uM.
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D77 is a potent inhibitor of HIV-1 integrase-LEDGF/p75 interaction binds to IN and IN(T125A) with Kd of 5.81 and 15.2 uM.
D77 affects the HIV-1 IN nuclear distribution thus exhibiting antiretroviral activity.
| M.Wt | 596.4458 | |
| Formula | C28H22BrNO7S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Du L, et al. Biochem Biophys Res Commun. 2008 Oct 10;375(1):139-44.
2. Li P, et al. J Biomol Struct Dyn. 2011 Oct;29(2):311-23.
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