Chemical Structure : DAA-1106
CAS No.: 220551-92-8
Catalog No.: PC-45756Not For Human Use, Lab Use Only.
DAA-1106 is a potent, selective agonist of PBR/TSPO that inhibits [3H]PK 11195 binding to crude mitochondrial preparations of rat whole brain with IC50 of 0.92 nM.
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DAA-1106 is a potent, selective agonist of PBR/TSPO that inhibits [3H]PK 11195 binding to crude mitochondrial preparations of rat whole brain with IC50 of 0.92 nM.
DAA-1106 significantly increases sleeping time in hexobarbital-induced anesthesia.
DAA-1106 has anxiolytic effects with no affect for spontaneous locomotor activity in mice; orally active.
| M.Wt | 395.4235 | |
| Formula | C23H22FNO4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 35 mg/mL |
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| Chemical Name/SMILES |
Acetamide, N-[(2,5-dimethoxyphenyl)methyl]-N-(5-fluoro-2-phenoxyphenyl)- |
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1. Okuyama S, et al. Life Sci. 1999;64(16):1455-64.
2. Chaki S, et al. Eur J Pharmacol. 1999 Apr 29;371(2-3):197-204.
3. Okubo T, et al. Bioorg Med Chem. 2004 Jan 15;12(2):423-38.

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