DAC-001 | HDAC1 activator | Probechem Biochemicals

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Chemical Structure : DAC-001

DAC-001 (Deacetylase-activating compound)

Catalog No.: PC-25166Not For Human Use, Lab Use Only.

DAC-001 is a small molecule, cell-active activator of HDAC1, exhibits dose-dependent activation of HDAC1 in vitro in a microfluidics-based assay at 5-10 uM, displayes significant protection against DNA breaks.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	366.44
Formula	C20H18N2O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((4-(5-(hydroxymethyl)furan-2-yl)phenyl)carbamothioyl)-4-methylbenzamide

References

1. L.-H. Tsai, S.J. et al. Activators of Class i Histone Deacetlyases (Hdacs) and Uses Thereof (2013). WO 2013/016193 A2.

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DAC-001 (Deacetylase-activating compound)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

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