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Chemical Structure : DAN004
Catalog No.: PC-60941Not For Human Use, Lab Use Only.
DAN 004 is a small molecule Bax inhibitor that inhibits Bax/Bak oligomerization and prevents mitochondrial outer membrane permeabilization (MOMP) with IC50 of 0.7 uM.
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DAN 004 is a small molecule Bax inhibitor that inhibits Bax/Bak oligomerization and prevents mitochondrial outer membrane permeabilization (MOMP) with IC50 of 0.7 uM.
DAN 004 potently inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons, protects primary neurons against glutamate excitotoxicity.
| M.Wt | 494.433 | |
| Formula | C26H28BrN3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Cell Chem Biol. 2017 Apr 20;24(4):493-506.e5.
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