DAS-CHO-5-oCRBN

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Chemical Structure : DAS-CHO-5-oCRBN

Catalog No.: PC-21653Not For Human Use, Lab Use Only.

DAS-CHO-5-oCRBN is a potent and selective PROTAC for c-Src kinase with DC50 value of 62 nM in CAL148 cells.

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Biological Activity

DAS-CHO-5-oCRBN is a potent and selective PROTAC for c-Src kinase with DC50 value of 62 nM in CAL148 cells.

M.Wt	883.99
Formula	C45H45N11O7S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((6-(4-(2-(4-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)piperazin-1-yl)-2-oxoethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)-N-(2-methyl-4-phenoxyphenyl)thiazole-5-carboxamide

1. Mao W, et al. ACS Chem Biol. 2023 Dec 19. doi: 10.1021/acschembio.3c00548.