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DBCO-Amine

Chemical Structure : DBCO-Amine

CAS No.: 1255942-06-3

DBCO-Amine (DBCO amine)

Catalog No.: PC-70007Not For Human Use, Lab Use Only.

A simple DBCO-containing building block used to derivatize carboxyl groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) with DBCO moiety through a stable amide bond.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A simple DBCO-containing building block used to derivatize carboxyl groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) with DBCO moiety through a stable amide bond; A click chemistry tool used to conjugate DBCO-PEG4-MMAF to the introduced non-natural amino acid pAMF using a noncleavable linker.

Physicochemical Properties

M.Wt 276.339
Formula C18H16N2O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-Amino-1-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-1-propanone

References

1. Currier NV, et al. Mol Cancer Ther. 2016 Jun;15(6):1291-300.

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