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DBCO-NHS ester

Chemical Structure : DBCO-NHS ester

CAS No.: 1353016-71-3

DBCO-NHS ester (DBCO NHS ester)

Catalog No.: PC-70081Not For Human Use, Lab Use Only.

An amine-reactive NHS ester that provides easy attachment of the reactive moiety to almost any primary or secondary amine group, such as that of protein, peptide, or small molecule amine.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

An amine-reactive NHS ester that provides easy attachment of the reactive moiety to almost any primary or secondary amine group, such as that of protein, peptide, or small molecule amine; A click chemistry tool used to conjugate DBCO-PEG4-MMAF to the introduced non-natural amino acid pAMF using a noncleavable linker.

Physicochemical Properties

M.Wt 430.45
Formula C25H22N2O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Dibenz[b,f]azocine-5(6H)-butanoic acid,11,12-didehydro-γ-oxo-,2,5-dioxo-1-pyrrolidinyl es

References

1. Currier NV, et al. Mol Cancer Ther. 2016 Jun;15(6):1291-300.

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