Chemical Structure : DC661
CAS No.: 1872387-43-3
Catalog No.: PC-35838Not For Human Use, Lab Use Only.
DC661 (DC-661) is a novel dimeric chloroquine (CQ) that is capable of deacidifying the lysosome and inhibiting autophagy significantly better than HCQ, targets palmitoyl-protein thioesterase 1 (PPT1).
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DC661 (DC-661) is a novel dimeric chloroquine (CQ) that is capable of deacidifying the lysosome and inhibiting autophagy significantly better than HCQ, targets palmitoyl-protein thioesterase 1 (PPT1).
DC661 inhibits autophagy and causes significant impairment of tumor growth.
M.Wt | 552.59 | |
Formula | C31H39Cl2N5 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N1-(7-Chloroquinolin-4-yl)-N6-(6-((7-chloroquinolin-4-yl)amino)hexyl)-N6-methylhexane-1,6-diamine |
1. Rebecca VW, et al. Cancer Discov. 2018 Nov 15. pii: CD-18-0706. doi: 10.1158/2159-8290.CD-18-0706.
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