DCC-3116 | ULK1/2 inhibitor | Probechem Biochemicals

Chemical Structure : DCC-3116

Catalog No.: PC-72327Not For Human Use, Lab Use Only.

DCC-3116 (DCC3116) is a first-in-class, selective inhibitor of ULK1/2 kinases (IC50=4.7/35 nM) and autophagy.

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Biological Activity

DCC-3116 (DCC3116) is a first-in-class, selective inhibitor of ULK1/2 kinases (IC50=4.7/35 nM) and autophagy.

M.Wt	535.62
Formula	C26H36F3N7O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Month
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(3-((2-((2-ethyl-4-(4-methylpiperazin-1-yl)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)propyl)-1,4-oxazepan-5-one

1. Ghazi PC, et al. bioRxiv [Preprint]. 2024 Feb 8:2024.02.06.579200.
2. Patent WO2024050351 A1.