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DCCCyB

Chemical Structure : DCCCyB

CAS No.: 1236046-15-3

DCCCyB

Catalog No.: PC-61457Not For Human Use, Lab Use Only.

A potent, selective, orally available GlyT1 inhibitor with IC50 of 29 nM, demonstrates excellent in vivo occupancy of GlyT1 transporters in vivo..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A potent, selective, orally available GlyT1 inhibitor with IC50 of 29 nM, demonstrates excellent in vivo occupancy of GlyT1 transporters in vivo.

Physicochemical Properties

M.Wt 458.438
Formula C22H29Cl2NO3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2,4-dichloro-N-(((1s,4s)-1-(cyclopropylmethyl)-4-((cyclopropylmethyl)sulfonyl)cyclohexyl)methyl)benzamide

References

1. Blackaby WP, et al. ACS Med Chem Lett. 2010 Jun 25;1(7):350-4.

2. Yamamoto S, et al. Chem Pharm Bull (Tokyo). 2016;64(11):1630-1640.

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