DDB1 ligand-1 | DDB1 ligand | Probechem Biochemicals

Chemical Structure : DDB1 ligand-1

DDB1 ligand-1 (Compound 26)

Catalog No.: PC-26824Not For Human Use, Lab Use Only.

DDB1 ligand-1 is a small molecule ligand of E3 ligase adapter protein DDB1 with TR-FRET IC50 of 26 nM, blocks the canonical DCAF/HBx peptide binding site of DDB1.

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Biological Activity

DDB1 ligand-1 is a small molecule ligand of E3 ligase adapter protein DDB1 with TR-FRET IC50 of 26 nM, blocks the canonical DCAF/HBx peptide binding site of DDB1.

Physicochemical Properties

M.Wt	590.63
Formula	C32H32F2N4O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(3S,5S)-1-(4-(2,2-difluorobenzo[d][1,3]dioxol-4-yl)-5-isopropoxy-1-methyl-1H-benzo[d]imidazole-7-carbonyl)-N-methyl-5-phenylpiperidine-3-carboxamide

References

1. Reddy Guduru SK, et al. ACS Med Chem Lett. 2026 Mar 27;17(4):757-767.

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DDB1 ligand-1 (Compound 26)

Biological Activity

Physicochemical Properties

References

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