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DFMNTU

Chemical Structure : DFMNTU

CAS No.: 313391-88-7

DFMNTU

Catalog No.: PC-28443Not For Human Use, Lab Use Only.

DFMNTU is a small molecule casein kinase 2 (CK2) inhibitor with IC50 of 22 uM for CK2α, potently inhibits Yellow fever virus (YFV)-induced cytopathic effects with EC50 of 4.3 ug/mL(neutral red uptake) and 2.4 ug/mL (visual CPE assessment).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

DFMNTU is a small molecule casein kinase 2 (CK2) inhibitor with IC50 of 22 uM for CK2α, potently inhibits Yellow fever virus (YFV)-induced cytopathic effects with EC50 of 4.3 ug/mL(neutral red uptake) and 2.4 ug/mL (visual CPE assessment).

Physicochemical Properties

M.Wt 425.45
Formula C22H17F2N3O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-[4-(2- difluoromethoxyphenyl)- 5- methylthiazol- 2- yl]- 3-(naphthalen- 1- yl)urea

References

1. Demchenko A, et al. Eur J Pharm Sci. 2026 Oct 3:107679.

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