Chemical Structure : DG051
CAS No.:
929915-58-2
DG051
(DG-051;DG 051)
Catalog No. : PC-42712Not For Human Use, Lab Use Only.
DG051 (DG-051) is a potent, selective LTA4H (Leukotriene A4 hydrolase) inhibitor (IC50/Kd=47/25 nM) of leukotriene B4 biosynthesis.
Packing Price Stock Quantity 5 mg $138 In stock 0 1 2 3 4 5 10 mg $218 In stock 0 1 2 3 4 5 25 mg $388 In stock 0 1 2 3 4 5 50 mg $598 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4271201
Biological Activity
DG051 (DG-051) is a potent, selective LTA4H (Leukotriene A4 hydrolase) inhibitor (IC50/Kd=47/25 nM) of leukotriene B4 biosynthesis.
Physicochemical Properties
M.Wt
426.3335
Formula
C21H25Cl2NO4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 325 mg/mL
Chemical Name/SMILES
1-Pyrrolidinebutanoic acid, 2-[[4-(4-chlorophenoxy)phenoxy]methyl]-, hydrochloride (1:1), (2S)-
References
1. Sandanayaka V, et al. J Med Chem.
2. Enache LA, et al. Bioorg Med Chem Lett.
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