Catalog No.: PC-47044Not For Human Use, Lab Use Only.
DHMEQ (dehydroxymethylepoxyquinomicin) is an NF-κB inhibitor, inhibits TNF-α-induced activation of NF-κB, and inhibits the TNF-α-induced nuclear accumulation of p65, a component of NF-κB.
DHMEQ (dehydroxymethylepoxyquinomicin) is an NF-κB inhibitor, inhibits TNF-α-induced activation of NF-κB, and inhibits the TNF-α-induced nuclear accumulation of p65, a component of NF-κB.
DHMEQ also inhibited TNF-α-induced nuclear transport of green fluorescent protein-tagged p65.
DHMEQ was effective in suppressing rheumatoid arthritis in an in vivo model.
DHMEQ completely inhibited NFkappaB DNA binding activity in JCA-1 cells.
DHMEQ significantly inhibited pre-established JCA-1 s.c. tumor growth in nude mice without any side effects.
