Chemical Structure : DMP-777
CAS No.:
157341-41-8
DMP-777
(L-694458, DMP777)
Catalog No. : PC-45963Not For Human Use, Lab Use Only.
DMP-777 (L-694458, DMP777) is a potent, selective, and orally active human leukocyte elastase (HLE) inhibitor with IC50 of 23 nM.
Packing Price Stock Quantity 5 mg $158 In stock 0 1 2 3 4 5 10 mg $248 In stock 0 1 2 3 4 5 25 mg $428 In stock 0 1 2 3 4 5 50 mg Get quote 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4596301
Biological Activity
DMP-777 (L-694458, DMP777) is a potent, selective, and orally active human leukocyte elastase (HLE ) inhibitor with IC50 of 23 nM.
Physicochemical Properties
M.Wt
564.6725
Formula
C31H40N4O6
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
1-Azetidinecarboxamide, N-[(1R)-1-(1,3-benzodioxol-5-yl)butyl]-3,3-diethyl-2-[4-[(4-methyl-1-piperazinyl)carbonyl]phenoxy]-4-oxo-, (2S)-
References
1. Cvetovich RJ, et al. J Org Chem
2. Nozaki K, et al. Gastroenterology
3. Macdonald SJ, et al. J Med Chem
Contact Us
sales@probechem.com
