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DNA gyrase inhibitor 35

Chemical Structure : DNA gyrase inhibitor 35

CAS No.: 2088347-91-3

DNA gyrase inhibitor 35

Catalog No.: PC-24340Not For Human Use, Lab Use Only.

DNA gyrase inhibitor 35 is potent small molecule DNA gyrase inhibitor with IC50 of 1.2 μM of E.coli DNA gyrase, also shows low micromolar inhibition of E. coli topoisomerase IV and of the respective Staphylococcus aureus homologues.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

DNA gyrase inhibitor 35 is potent small molecule DNA gyrase inhibitor with IC50 of 1.2 μM of E.coli DNA gyrase, also shows low micromolar inhibition of E. coli topoisomerase IV and of the respective Staphylococcus aureus homologues.

Physicochemical Properties

M.Wt 396.18
Formula C15H11Cl2N5O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-((4-(3,4-dichloro-5-methyl-1H-pyrrole-2-carboxamido)phenyl)amino)-1,2,4-oxadiazole-3-carboxylic acid

References

1. Jakopin Ž, et al. Eur J Med Chem. 2017 Apr 21;130:171-184.

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