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Chemical Structure : DNS-pE
Catalog No.: PC-62599Not For Human Use, Lab Use Only.
DNS-pE (PHGDH Fluorescent Probe DNS-pE) is the first small molecule that can selectively label endogenous 3-phosphoglycerate dehydrogenase (PHGDH) from various mammalian cells.
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DNS-pE (PHGDH Fluorescent Probe DNS-pE) is the first small molecule that can selectively label endogenous 3-phosphoglycerate dehydrogenase (PHGDH) from various mammalian cells.
DNS-pE is highly fluorescent only upon irreversible covalent modification of PHGDH with an inhibitory property (in vitro Ki=7.4 uM).
| M.Wt | 261.339 | |
| Formula | C14H15NO2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Pan S, et al. Angew Chem Int Ed Engl. 2018 Jan 8;57(2):579-583.
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