DPI-287 | DOP agonist | Probechem Biochemicals

Chemical Structure : DPI-287

DPI-287 (DPI 287)

Catalog No.: PC-49552Not For Human Use, Lab Use Only.

DPI-287 is a small-molecule agonist of the δ-opioid receptor (DOP, DOR) with Ki vaule of 0.39 nM, shows 10-fold selectivity for DOP over MOP (Ki=3.17 nM).

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Biological Activity

DPI-287 is a small-molecule agonist of the δ-opioid receptor (DOP, DOR) with Ki vaule of 0.39 nM, shows 10-fold selectivity for DOP over MOP (Ki=3.17 nM).

Physicochemical Properties

M.Wt	485.67
Formula	C31H39N3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-((R)-((2S,5R)-4-benzyl-2,5-dimethylpiperazin-1-yl)(3-hydroxyphenyl)methyl)-N,N-diethylbenzamide

References

1. Tobias Claff, et al. Sci Adv. 2019 Nov 27;5(11):eaax9115.

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DPI-287 (DPI 287)

Biological Activity

Physicochemical Properties

References

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