Chemical Structure : DREADD agonist compound 21
CAS No.: 56296-18-5
Catalog No.: PC-42096Not For Human Use, Lab Use Only.
DREADD agonist compound 21 (hM3Dq agonist) is a potent, selective human muscarinic acetylcholine M3 receptor (hM3Dq) full agonist with EC50 of 1.7 nM.
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DREADD agonist compound 21 (hM3Dq agonist) is a potent, selective human muscarinic acetylcholine M3 receptor (hM3Dq) full agonist with EC50 of 1.7 nM.
hM3Dq-agonist-21 displays 3.5-fold selective over H1, 40-fold selective over 5HT2A, 100-fold selective over 5HT2C, 165-fold selective over α1A, and inactive at native human M3 receptor (hM3).
| M.Wt | 278.3516 | |
| Formula | C17H18N4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 78 mg/mL |
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| Chemical Name/SMILES |
5H-Dibenzo[b,e][1,4]diazepine, 11-(1-piperazinyl)- |
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1. Chen X, et al. ACS Chem Neurosci. 2015 Mar 18;6(3):476-84.

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