DRP1-MiD49 inhibitor 4a

Chemical Structure : DRP1-MiD49 inhibitor 4a

Catalog No.: PC-26859Not For Human Use, Lab Use Only.

DRP1-MiD49 inhibitor 4a is a potent allosteric DRP1 inhibitor, disrupts protein-protein interaction of DRP1/MiD49 with IC50 of 0.1 uM, inhibits mitochondria fragmentation in vitro.

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Biological Activity

DRP1-MiD49 inhibitor 4a is a potent allosteric DRP1 inhibitor, disrupts protein-protein interaction of DRP1/MiD49 with IC50 of 0.1 uM, inhibits mitochondria fragmentation in vitro.

Physicochemical Properties

M.Wt	359.43
Formula	C22H21N3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-(azetidin-1-yl)-2-phenylquinolin-6-yl)oxetane-3-carboxamide

References

1. Takeru Furuya, et al. ACS Med Chem Lett. 2023 Jul 24;14(8):1095-1099.

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