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DRP1i2

Chemical Structure : DRP1i2

CAS No.:

DRP1i2

Catalog No.: PC-27924Not For Human Use, Lab Use Only.

DRP1i2 is a small-molecule dynamin-related protein 1 (Drp1) inhibitor targeting a conserved domain, mitigates doxorubicin-induced cardiotoxicity while preserving anticancer efficacy.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

DRP1i2 is a small-molecule dynamin-related protein 1 (Drp1) inhibitor targeting a conserved domain, mitigates doxorubicin-induced cardiotoxicity while preserving anticancer efficacy.

Physicochemical Properties

M.Wt 312.37
Formula C22H16O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(6H-benzo[c]chromen-6-yl)-1H-inden-1-ol

References

1. Deng, Y., Bass-Stringer, S., Bond, S.T. et al. The Drp1 inhibitor DRP1i2 confers cardioprotection against doxorubicin-induced cardiotoxicity. Cell Death Discov. (2026).

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