Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Others-Mitochondrial Permeability Transition Pore (mPTP)-DS44170716
DS44170716

Chemical Structure : DS44170716

CAS No.: 486993-62-8

Add to Favorites

DS44170716 (DS-44170716, DS 44170716)

Catalog No.: PC-60363Not For Human Use, Lab Use Only.

DS44170716 is a small molecule MPT (mitochondrial permeability transition) inhibitor of that inhibits Ca2+-induced MPT in rat liver isolated mitochondria.

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    DS44170716 is a small molecule MPT (mitochondrial permeability transition) inhibitor of that inhibits Ca2+-induced MPT in rat liver isolated mitochondria.
    DS44170716 protects human liver HepG2 cells from Ca2+-induced death with a level of protection similar to cyclosporin A。
    DS44170716 potently inhibits mitochondrial complex III activities and weakly inhibits complex IV and V activities.

    Physicochemical Properties

    M.Wt 384.273
    Formula C20H18BrNO2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (3aS,4R,9bR)-8-bromo-4-(p-tolyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-6-carboxylic acid

    References

    1. Kon N, et al. Sci Rep. 2017 Jun 20;7(1):3864.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: