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Chemical Structure : DS44170716
Catalog No.: PC-60363Not For Human Use, Lab Use Only.
DS44170716 is a small molecule MPT (mitochondrial permeability transition) inhibitor of that inhibits Ca2+-induced MPT in rat liver isolated mitochondria.
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DS44170716 is a small molecule MPT (mitochondrial permeability transition) inhibitor of that inhibits Ca2+-induced MPT in rat liver isolated mitochondria.
DS44170716 protects human liver HepG2 cells from Ca2+-induced death with a level of protection similar to cyclosporin A。
DS44170716 potently inhibits mitochondrial complex III activities and weakly inhibits complex IV and V activities.
| M.Wt | 384.273 | |
| Formula | C20H18BrNO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kon N, et al. Sci Rep. 2017 Jun 20;7(1):3864.
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