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DYR530

Chemical Structure : DYR530

CAS No.: 2410298-39-2

DYR530 (DYR-530)

Catalog No.: PC-23236Not For Human Use, Lab Use Only.

DYR530 is a potent, selective inhibitor of DYRK1 with Kd of 0.91 nM (DYRK1A).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

DYR530 is a potent, selective inhibitor of DYRK1 with Kd of 0.91 nM (DYRK1A).

Physicochemical Properties

M.Wt 417.49
Formula C23H24FN7
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
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Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(3-(3-fluoro-4-(4-methylpiperazin-1-yl)phenyl)-2-methyl-3H-imidazo[4,5-b]pyridin-5-yl)pyridin-2-amine

References

1. Wilms G, et al. J Med Chem. 2024 Oct 10;67(19):17259-17289.

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