Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : DZ-2384
Catalog No.: PC-35304Not For Human Use, Lab Use Only.
DZ-2384 (DZ2384) is a microtubule-targeting agent, exhibits potent antitumor activity in models of multiple cancer types.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
DZ-2384 (DZ2384) is a microtubule-targeting agent, exhibits potent antitumor activity in models of multiple cancer types.
DZ-2384 binds the vinca domain of tubulin, DZ-2384 has potent antitumor activity as a single agent and in combination with gemcitabine both in vitro and in vivo, enhances gemcitabine activity in mouse models of pancreatic cancer.
| M.Wt | 645.677 | |
| Formula | C34H36FN5O7 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Ding H, et al. Angew Chem Int Ed Engl. 2015 Apr 13;54(16):4818-22.
2. Wieczorek M, et al. Sci Transl Med. 2016 Nov 16;8(365):365ra159.
3. Bernier C, et al. Anticancer Drugs. 2018 Jun 22. doi: 10.1097/CAD.0000000000000653.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
