DZ-865B | BCL6 PROTAC | Probechem Biochemicals

Chemical Structure : DZ-865B

DZ-865B (DZ865B)

Catalog No.: PC-26284Not For Human Use, Lab Use Only.

DZ-865B is a selective BCL6 degrader with DC50 of 2.7 uM and 4.7 uM in DLBCL cell lines OCI-LY-1 and SU-DHL-4 respectively, effectively suppresses DLBCL cell growth.

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Biological Activity

DZ-865B is a selective BCL6 degrader with DC50 of 2.7 uM and 4.7 uM in DLBCL cell lines OCI-LY-1 and SU-DHL-4 respectively, effectively suppresses DLBCL cell growth.

Physicochemical Properties

M.Wt	865.94
Formula	C43H44FN9O8S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(cyclopent-1-en-1-yl)-N-(4-((2-(4-(3-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)ethoxy)propanoyl)piperazin-1-yl)-5-fluoropyrimidin-4-yl)amino)-2-methoxyphenyl)thiophene-2-carboxamide

References

1. Yanfeng Wang, et al. Oncol Res. 2026 Feb 24;34(3):23.

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DZ-865B (DZ865B)

Biological Activity

Physicochemical Properties

References

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