Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Dabigatran etexilate
CAS No.: 211915-06-9
Catalog No.: PC-42506Not For Human Use, Lab Use Only.
Dabigatran etexilate (BIBR1048) is a prodrug of BIBR-953, which is a potent nonpeptide thrombin inhibitor with Ki of 4.5 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $98 | In stock | |
| 100 mg | $148 | In stock | |
| 250 mg | $258 | In stock | |
| 1 g | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Dabigatran etexilate (BIBR1048) is a prodrug of BIBR-953, which is a potent nonpeptide thrombin inhibitor with Ki of 4.5 nM.
BIBR1048 is 10-fold less potent for Trypsin and no activity against Factor Xa, Plasmin, tPA and activated protein C.
BIBR1048 exhibits strong and long-lasting anticoagulant effects ex vivo and strong oral activity in different animal species.
| M.Wt | 627.7332 | |
| Formula | C34H41N7O5 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
b-Alanine, N-[[2-[[[4-[[[(hexyloxy)carbonyl]amino]iminomethyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-, ethyl ester |
|
1. Hauel NH, et al. J Med Chem. 2002 Apr 25;45(9):1757-66.
2. Wienen W, et al. Thromb Haemost. 2007 Jul;98(1):155-62.
3. Baetz BE, et al. Pharmacotherapy. 2008 Nov;28(11):1354-73.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
