Chemical Structure : Dacetuzumab
CAS No.:
Catalog No.: PC-Ab1099Not For Human Use, Lab Use Only.
Dacetuzumab (SGN-40, huS2C6) is a humanized anti-CD40 monoclonal antibody that specifically binds to and works against a molecule called a CD40 receptor. Dacetuzumab has been used in trials studying the treatment of Multiple Myeloma, Non-Hodgkin Lymphoma, Leukemia, Lymphocytic, Chronic, and Lymphoma, Large B-Cell, Diffuse. It is a humanized anti-CD40 antibody and induces cytotoxicity in human multiple myeloma cells. Dacetuzumab demonstrated antitumor activity in relapsed/refractory diffuse large
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Dacetuzumab (SGN-40, huS2C6) is a humanized anti-CD40 monoclonal antibody that specifically binds to and works against a molecule called a CD40 receptor. Dacetuzumab has been used in trials studying the treatment of Multiple Myeloma, Non-Hodgkin Lymphoma, Leukemia, Lymphocytic, Chronic, and Lymphoma, Large B-Cell, Diffuse. It is a humanized anti-CD40 antibody and induces cytotoxicity in human multiple myeloma cells. Dacetuzumab demonstrated antitumor activity in relapsed/refractory diffuse large B-cell lymphoma (DLBCL). Dacetuzumab induces ADCC and ADCP via interaction with Fc receptors on T cells, NK cells, monocytes, and macrophages.
M.Wt | ||
Formula | Human IgG1-Kappa | |
Appearance | Solid | |
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Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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