Chemical Structure : Dalosirvat
CAS No.: 1360540-81-3
Catalog No.: PC-38354Not For Human Use, Lab Use Only.
Dalosirvat (SM04554) is a small-molecule Wnt pathway modulator, activates Wnt with IC50 of 28-29 nM, with potential topical treatment for androgenetic alopecia.
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Dalosirvat (SM04554) is a small-molecule Wnt pathway modulator, activates Wnt with IC50 of 28-29 nM, with potential topical treatment for androgenetic alopecia.
SM04554 increased total and nuclear β-catenin, versican and Ki-67 specifically in hair follicles.
SM04554 increased follicle numbers and hair growth.
M.Wt | 296.322 | |
Formula | C18H16O4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-4-phenylbutane-1,4-dione |
1. V. Deshmukh, et al. DOI: https://doi.org/10.1016/j.jid.2017.02.735
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