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Dantrolene sodium hemiheptahydrate

Chemical Structure : Dantrolene sodium hemiheptahydrate

CAS No.: 24868-20-0

Dantrolene sodium hemiheptahydrate (Dantrolene sodium hydrate)

Catalog No.: PC-43100Not For Human Use, Lab Use Only.

Dantrolene is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells, inhibits Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors.

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Biological Activity

Dantrolene sodium hemiheptahydrate is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells, inhibits Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors.

Physicochemical Properties

M.Wt 400.30
Formula C14H17N4NaO8.5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 33 mg/mL

Chemical Name/SMILES

2,4-Imidazolidinedione, 1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-, sodium salt, hydrate (2:2:7)

References

1. Zucchi R, et al. Pharmacol Rev. 1997 Mar;49(1):1-51.

2. Barker K, et al. Clin Toxicol (Phila). 2006;44(3):351.

3. Ellis KO, et al. J Pharm Sci. 1973 Jun;62(6):948-51.

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