Chemical Structure : Dapivirine
CAS No.: 244767-67-7
Catalog No.: PC-23582Not For Human Use, Lab Use Only.
Dapivirine (TMC120, R147681) is a potent, HIV-1 nonnucleoside reverse transcriptase inhibitor (NNRTI) with IC50 of 24 nM, inhibits syncytium formation of HIV-1 IIIB-infected CEM T cells with EC50 of 1 nM, shows high activity against wild-type and mutant HIV.
Packing | Price | Stock | Quantity |
---|---|---|---|
10 mg | $78 | In stock | |
25 mg | $128 | In stock |
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Dapivirine (TMC120, R147681) is a potent, HIV-1 nonnucleoside reverse transcriptase inhibitor (NNRTI) with IC50 of 24 nM, inhibits syncytium formation of HIV-1 IIIB-infected CEM T cells with EC50 of 1 nM, shows high activity against wild-type and mutant HIV.
M.Wt | 329.41 | |
Formula | C20H19N5 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
4-((4-(Mesitylamino)pyrimidin-2-yl)amino)benzonitrile |
1. Van Herrewege Y, et al. Antimicrob Agents Chemother. 2004 Jan;48(1):337-9.
2. Njai HF, et al. Antivir Ther. 2005;10(2):255-62.
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