Dapivirine | NNRTI | Probechem Biochemicals

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Chemical Structure : Dapivirine

CAS No.: 244767-67-7

Dapivirine (TMC120, R147681)

Catalog No.: PC-23582Not For Human Use, Lab Use Only.

Dapivirine (TMC120, R147681) is a potent, HIV-1 nonnucleoside reverse transcriptase inhibitor (NNRTI) with IC50 of 24 nM, inhibits syncytium formation of HIV-1 IIIB-infected CEM T cells with EC50 of 1 nM, shows high activity against wild-type and mutant HIV.

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25 mg	$128	In stock

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Physicochemical Properties

M.Wt	329.41
Formula	C20H19N5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-((4-(Mesitylamino)pyrimidin-2-yl)amino)benzonitrile

References

1. Van Herrewege Y, et al. Antimicrob Agents Chemother. 2004 Jan;48(1):337-9.

2. Njai HF, et al. Antivir Ther. 2005;10(2):255-62.

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Dapivirine (TMC120, R147681)

Biological Activity

Physicochemical Properties

References

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