Daratumumab
(Anti-human CD38 mAb, human IgG1-Kappa)
Catalog No.: PC-Ab1043Not For Human Use, Lab Use Only.
Daratumumab is a human monoclonal antibody that targets CD38, depletes plasma cells and is approved for the treatment of multiple myeloma. Daratumumab inhibits the growth of CD38 expressing tumor cells and induces apoptosis (cell death) directly through mediated cross linking and by immune mediated tumor cell lysis through complement dependent cytotoxicity, antibody cell mediated cytotoxicity, and antibody dependent cellular phagocytosis..
Daratumumab is a human monoclonal antibody that targets CD38, depletes plasma cells and is approved for the treatment of multiple myeloma. Daratumumab inhibits the growth of CD38 expressing tumor cells and induces apoptosis (cell death) directly through mediated cross linking and by immune mediated tumor cell lysis through complement dependent cytotoxicity, antibody cell mediated cytotoxicity, and antibody dependent cellular phagocytosis.
Physicochemical Properties
M.Wt
Formula
Human IgG1-Kappa
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
PBS, pH 7.0
Contains no stabilizers or preservatives
