Dasolampanel |CAS:503294-13-1 Probechem Biochemicals

Chemical Structure : Dasolampanel

Dasolampanel (NGX426)

Catalog No.: PC-61714Not For Human Use, Lab Use Only.

Dasolampanel (NGX426) is an orally bioavailable, competitive antagonist of the AMPA-kainate receptors for the treatment of chronic pain conditions including neuropathic pain and migraine..

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Biological Activity

Dasolampanel (NGX426) is an orally bioavailable, competitive antagonist of the AMPA-kainate receptors for the treatment of chronic pain conditions including neuropathic pain and migraine.

Physicochemical Properties

M.Wt	377.825
Formula	C17H20ClN5O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(3S,4aS,6S,8aR)-6-(3-chloro-2-(1H-tetrazol-5-yl)phenoxy)-decahydroisoquinoline-3-carboxylic acid

References

1. Wallace MS, et al. Pain Med. 2012 Dec;13(12):1601-10.

2. Martinez-Perez JA, et al. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6463-6.

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Dasolampanel (NGX426)

Biological Activity

Physicochemical Properties

References

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