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Dasolampanel

Chemical Structure : Dasolampanel

CAS No.: 503294-13-1

Dasolampanel (NGX426)

Catalog No.: PC-61714Not For Human Use, Lab Use Only.

Dasolampanel (NGX426) is an orally bioavailable, competitive antagonist of the AMPA-kainate receptors for the treatment of chronic pain conditions including neuropathic pain and migraine..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Dasolampanel (NGX426) is an orally bioavailable, competitive antagonist of the AMPA-kainate receptors for the treatment of chronic pain conditions including neuropathic pain and migraine.

    Physicochemical Properties

    M.Wt 377.825
    Formula C17H20ClN5O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (3S,4aS,6S,8aR)-6-(3-chloro-2-(1H-tetrazol-5-yl)phenoxy)-decahydroisoquinoline-3-carboxylic acid

    References

    1. Wallace MS, et al. Pain Med. 2012 Dec;13(12):1601-10.

    2. Martinez-Perez JA, et al. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6463-6.

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