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Chemical Structure : Dasotraline hydrochloride
Catalog No.: PC-43257Not For Human Use, Lab Use Only.
Dasotraline (SEP-225289) is a novel triple reuptake inhibitor, antidepressant agent that blocks norepinephrine (NE), dopamine (DA) and serotonin (5-HT) transporters with IC50 values of 4, 6, and 11 nM, respectively.
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Dasotraline (SEP-225289) is a novel triple reuptake inhibitor, antidepressant agent that blocks norepinephrine (NE), dopamine (DA) and serotonin (5-HT) transporters with IC50 values of 4, 6, and 11 nM, respectively; demonstrates potential for the treatment of attention-deficit/hyperactivity disorder (ADHD).
| M.Wt | 328.6639 | |
| Formula | C16H16Cl3N | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 31 mg/mL |
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1. Koblan KS, et al. Neuropsychopharmacology. 2015 Nov;40(12):2745-52.
2. Hopkins SC, et al. Clin Drug Investig. 2016 Feb;36(2):137-46.
3. Guiard BP, et al. Int J Neuropsychopharmacol. 2011 Mar;14(2):211-23.
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