Daxdilimab | Anti-ILT7 (CD85g, LILRA4) mAb

Chemical Structure : Daxdilimab

Daxdilimab (HZN-7734, VBI 7734)

Catalog No.: PC-38814Not For Human Use, Lab Use Only.

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Biological Activity

Daxdilimab (HZN-7734) is a fully human monoclonal antibody that binds to the ILT7 protein on the surface of plasmacytoid dendritic cells (pDCs) and recruits effector cells, such as natural killer (NK) cells, that help to kill pDCs.
ILT7 (CD85g, LILRA4) is a protein found specifically on pDCs, pDC depletion with daxdilimab prevents the production of type 1 interferons, pro-inflammatory cytokines.
Isotype: IgG1-lambda.
Anti-[human LILRA4 (leukocyte immunoglobulin like receptor A4, ILT7, CD85g)], human monoclonal antibody.

Physicochemical Properties

M.Wt
Formula
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES

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Daxdilimab (HZN-7734, VBI 7734)

Biological Activity

Physicochemical Properties

References

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