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Dehydromutactin

Chemical Structure : Dehydromutactin

CAS No.: 823803-77-6

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Dehydromutactin

Catalog No.: PC-60908Not For Human Use, Lab Use Only.

Dehydromutactin is a small molecule inhibitor of RNA-binding protein Hu protein R (HuR) that interferes the HuR homodimerization with Kd of 40 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Dehydromutactin is a small molecule inhibitor of RNA-binding protein Hu protein R (HuR) that interferes the HuR homodimerization with Kd of 40 nM.
    Dehydromutactin interferes with HuR RNA binding, HuR trafficking, cytokine expression and T-cell activation.
    Dehydromutactin is a valuable tool for studying HuR function.

    Physicochemical Properties

    M.Wt 284.267
    Formula C16H12O5
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    6-(4,5-dihydroxy-2-methylnaphthalen-1-yl)-4-hydroxypyran-2-one

    References

    1. Meisner NC, et al. Nat Chem Biol. 2007 Aug;3(8):508-15.

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