Chemical Structure : Delavirdine
CAS No.: 136817-59-9
Catalog No.: PC-42658Not For Human Use, Lab Use Only.
Delavirdine is a potent HIV-1 reverse transcriptase inhibitor with IC50 of 0.26 uM for recombinant HIV-1 RT.
Packing | Price | Stock | Quantity |
---|---|---|---|
10 mg | $48 | In stock | |
25 mg | $88 | In stock | |
100 mg | $158 | In stock | |
250 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Delavirdine is a potent HIV-1 reverse transcriptase inhibitor with IC50 of 0.26 uM for recombinant HIV-1 RT.
Delavirdine exhibits IC50>440 uM for DNA polymerases α and δ.
Delavirdine blocks the replication in peripheral blood lymphocytes of 25 primary HIV-1 isolates and has low cellular cytotoxicity.
Delavirdine retains significant activity against mutant RTs (K103N, Y181C).
M.Wt | 456.5611 | |
Formula | C22H28N6O3S | |
Appearance | Solid | |
Storage |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
Methanesulfonamide, N-[2-[[4-[3-[(1-methylethyl)amino]-2-pyridinyl]-1-piperazinyl]carbonyl]-1H-indol-5-yl]- |
1. Dueweke TJ, et al. Antimicrob Agents Chemother. 1993 May;37(5):1127-31.
2. Romero DL, et al. J Med Chem. 1993 May 14;36(10):1505-8.
3. Olmsted RA, et al. J Virol. 1996 Jun;70(6):3698-705.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright