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Chemical Structure : Delavirdine
CAS No.: 136817-59-9
Catalog No.: PC-42658Not For Human Use, Lab Use Only.
A potent HIV-1 reverse transcriptase inhibitor with IC50 of 0.26 uM for recombinant HIV-1 RT.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $56 | In stock | |
| 100 mg | $64 | In stock | |
| 200 mg | $112 | In stock |
Bulk size, bulk discount!
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A potent HIV-1 reverse transcriptase inhibitor with IC50 of 0.26 uM for recombinant HIV-1 RT; exhibits IC50>440 uM for DNA polymerases α and δ; blocks the replication in peripheral blood lymphocytes of 25 primary HIV-1 isolates and has low cellular cytotoxicity; retains significant activity against mutant RTs (K103N, Y181C).
HIV Infection
Approved
| M.Wt | 456.5611 | |
| Formula | C22H28N6O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Methanesulfonamide, N-[2-[[4-[3-[(1-methylethyl)amino]-2-pyridinyl]-1-piperazinyl]carbonyl]-1H-indol-5-yl]- |
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1. Dueweke TJ, et al. Antimicrob Agents Chemother. 1993 May;37(5):1127-31.
2. Romero DL, et al. J Med Chem. 1993 May 14;36(10):1505-8.
3. Olmsted RA, et al. J Virol. 1996 Jun;70(6):3698-705.
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