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Chemical Structure : Delpazolid
CAS No.: 1219707-39-7
Catalog No.: PC-60037Not For Human Use, Lab Use Only.
Delpazolid (LCB01-0371) is an oxazolidinone antibiotic that shows good antibacterial activity (MSSA MIC50=1 ug/mL).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $218 | In stock | |
| 50 mg | $358 | In stock | |
| 100 mg | Get quote |
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Delpazolid (LCB01-0371) is an oxazolidinone antibiotic that shows good antibacterial activity (MSSA MIC50=1 ug/mL).
Delpazolid (LCB01-0371) potently inhibits MSSA and MRSA clinical isolates with MIC of 0.5-2 and 0.5-4 ug/mL, respectively.
Delpazolid (LCB01-0371) shows more-potent protective effects (MSSA ED50=4.53 mg/kg) than Linezolid against systemic infections caused by Gram-positive and Gram-negative bacteria in mice model.
| M.Wt | 308.313 | |
| Formula | C14H17FN4O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(5R)-3-[3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one |
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1. Jeong JW, et al. Antimicrob Agents Chemother. 2010 Dec;54(12):5359-62.
2. Kim TS, et al. Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e02752-16.
3. Choi Y, et al. J Antimicrob Chemother. 2017 Oct 23. doi: 10.1093/jac/dkx367.
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