Catalog No.: PC-26073Not For Human Use, Lab Use Only.
Desmethoxyyangonin is one of the six major kavalactones found in the Piper methysticum (kava) plant, is a selective inhibitor of monoamine oxidase-B (MAO-B) with IC50 of 0.123 uM, also demonstrates CB2 agonist activity, exerts anti-inflammatory effects by inhibiting Jak2/STAT3 and IKK signaling pathways.
Desmethoxyyangonin is one of the six major kavalactones found in the Piper methysticum (kava) plant, is a selective inhibitor of monoamine oxidase-B (MAO-B) with IC50 of 0.123 uM, also demonstrates CB2 agonist activity, exerts anti-inflammatory effects by inhibiting Jak2/STAT3 and IKK signaling pathways.
Physicochemical Properties
M.Wt
228.25
Formula
C14H12O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(E)-4-Methoxy-6-styryl-2H-pyran-2-one
References
1. Chaurasiya ND, et al. Evid Based Complement Alternat Med. 2017;2017:4018724.
2. Chou TW, et al. PLoS One. 2013 Oct 15;8(10):e77626.
