Deutetrabenazine | VMAT2 inhibitor | Probechem Biochemicals

Chemical Structure : Deutetrabenazine

CAS No.: 1392826-25-3

Deutetrabenazine (Tetrabenazine-d6)

Catalog No.: PC-24213Not For Human Use, Lab Use Only.

Deutetrabenazine is an inhibitor of vesicular monoamine transporter type 2 (VMAT2), depletes presynaptic dopamine and is useful in the treatment of hyperkinetic movement disorders.

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Biological Activity

Deutetrabenazine is an inhibitor of vesicular monoamine transporter type 2 (VMAT2), depletes presynaptic dopamine and is useful in the treatment of hyperkinetic movement disorders.

Physicochemical Properties

M.Wt	323.47
Formula	C19H21D6NO3:
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(3R,11bR)-3-Isobutyl-9,10-bis(methoxy-d3)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one

References

1. Jankovic J, et al. Tremor Other Hyperkinet Mov (N Y). 2016 Nov 7;6:422.

2. Fernandez HH, et al. Neurology. 2017 May 23;88(21):2003-2010.

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Deutetrabenazine (Tetrabenazine-d6)

Biological Activity

Physicochemical Properties

References

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