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Dicoumarol

Chemical Structure : Dicoumarol

CAS No.: 66-76-2

Dicoumarol (Dicumarol)

Catalog No.: PC-23295Not For Human Use, Lab Use Only.

Dicoumarol (Dicumarol) is an inhibitor of both NAD(P)H:quinone oxidoreductase 1 (NQO1) and PDK1 with IC50 of 0.37 and 19.42 uM respectively, also is a potent VRAC inhibitor.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Dicoumarol (Dicumarol) is an inhibitor of both NAD(P)H:quinone oxidoreductase 1 (NQO1) and PDK1 with IC50 of 0.37 and 19.42 uM respectively, also is a potent VRAC inhibitor.

Physicochemical Properties

M.Wt 336.30
Formula C19H12O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3,3'-Methylenebis(4-hydroxy-2H-chromen-2-one)

References

1. Chu J, et al. bioRxiv [Preprint]. 2023 Jan 8:2023.01.08.523161.

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