Difamilast | PDE4B inhibitor | Probechem Biochemicals

Chemical Structure : Difamilast

CAS No.: 937782-05-3

Catalog No.: PC-61372Not For Human Use, Lab Use Only.

Difamilast (OPA-15406) is a novel potent, selective phosphodiesterase IV (PDE4) inhibitor with preference for PDE4B (IC50=11.2 nM).

Packing	Price	Stock
5 mg	$128	In stock
10 mg	$198	In stock
25 mg	$328	In stock
50 mg	$528	In stock
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Biological Activity

Difamilast (OPA-15406) is a novel potent, selective phosphodiesterase IV (PDE4) inhibitor with preference for PDE4B (IC50=11.2 nM).

M.Wt	446.451
Formula	3H24F2N2O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-({2-[4-(difluoromethoxy)-3-(propan-2-yloxy)phenyl]-1,3-oxazol-4-yl}methyl)-2-ethoxybenzamide

1. Hanifin JM, et al. J Am Acad Dermatol. 2016 Aug;75(2):297-305.