Chemical Structure : Difelikefalin
CAS No.: 1024828-77-0
Catalog No.: PC-23828Not For Human Use, Lab Use Only.
Difelikefalin (CR-845; FE-202845) is a potent, selective and peripherally-restricted kappa opioid receptor (KOR) agonist, prevents [3H]diprenorphine binding to KOR with IC50 of 1.16 nM, and binding Kd of 0.23 nM.
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Difelikefalin (CR-845; FE-202845) is a potent, selective and peripherally-restricted kappa opioid receptor (KOR) agonist, prevents [3H]diprenorphine binding to KOR with IC50 of 1.16 nM, and binding Kd of 0.23 nM.
M.Wt | 679.86 | |
Formula | C36H53N7O6 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
4-Piperidinecarboxylic acid, N1-(D-phenylalanyl-D-phenylalanyl-D-leucyl-D-lysyl)-4-amino- |
1. Viscusi ER, et al. Clin Transl Sci. 2021 Sep;14(5):1886-1893.
2. Wang X, et al. Front Pharmacol. 2021 Nov 16;12:773204.
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