Dihydrokainic acid | GLT-1 antagonist, EAAT2 inhibitor

Chemical Structure : Dihydrokainic acid

Dihydrokainic acid (DHK)

Catalog No.: PC-24904Not For Human Use, Lab Use Only.

Dihydrokainic acid (DHK) is a glutamate transporter 1 (GLT-1) antagonist and selective inhibitor of EAAT2, does not significantly affect transport by EAAT1/EAAT3.

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Biological Activity

Dihydrokainic acid (DHK) is a glutamate transporter 1 (GLT-1) antagonist and selective inhibitor of EAAT2, does not significantly affect transport by EAAT1/EAAT3.

Physicochemical Properties

M.Wt	215.25
Formula	C10H17NO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S,3S,4R)-3-(carboxymethyl)-4-isopropylpyrrolidine-2-carboxylic acid

References

1. Arriza JL, et al. J Neurosci. 1994 Sep;14(9):5559-69.

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Dihydrokainic acid (DHK)

Biological Activity

Physicochemical Properties

References

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