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Dilmapimod

Chemical Structure : Dilmapimod

CAS No.: 444606-18-2

Dilmapimod (SB-681323; GW 681323)

Catalog No.: PC-21599Not For Human Use, Lab Use Only.

SB-681323 is a potent and selective p38 MAPK inhibitor, potentially suppresses inflammation in chronic obstructive pulmonary disease.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Dilmapimod (SB-681323) is a potent and selective p38 MAPK inhibitor, potentially suppresses inflammation in chronic obstructive pulmonary disease.

Physicochemical Properties

M.Wt 456.43
Formula C23H19F3N4O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

8-(2,6-Difluorophenyl)-2-((1,3-dihydroxypropan-2-yl)amino)-4-(4-fluoro-2-methylphenyl)pyrido[2,3-d]pyrimidin-7(8H)-one

References

1. Anand P, et al. Eur J Pain. 2011 Nov;15(10):1040-8.

2. Sarov-Blat L, et al. Arterioscler Thromb Vasc Biol. 2010 Nov;30(11):2256-63.

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