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Diltiazem hydrochloride

Chemical Structure : Diltiazem hydrochloride

CAS No.: 33286-22-5

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Diltiazem hydrochloride (CRD-401)

Catalog No.: PC-44015Not For Human Use, Lab Use Only.

A postsynaptic muscle relaxant that inhibits Ca2+ ions release from sarcoplasmic reticulum stores.

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5 g $88 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A postsynaptic muscle relaxant that inhibits Ca2+ ions release from sarcoplasmic reticulum stores; antagonizes ryanodine receptors; can prevent cell death in neural progenitor cells derived from Wolfram syndrome iPS cells.

Hypertension

Approved

Physicochemical Properties

M.Wt 450.9788
Formula C22H27ClN2O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-, hydrochloride (1:1), (2S,3S)-

References

1. Lu S, et al. Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):E5292-301.

2. Zucchi R, et al. Pharmacol Rev. 1997 Mar;49(1):1-51.

3. Krause T, et al. Anaesthesia. 2004 Apr;59(4):364-73.

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