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Diminazene aceturate

Chemical Structure : Diminazene aceturate

CAS No.: 908-54-3

Diminazene aceturate (Diminazene diaceturate)

Catalog No.: PC-62647Not For Human Use, Lab Use Only.

Diminazene aceturate is an anti-infective agent, also is a slow pore blocker of acid-sensing ion channel 1a (ASIC1a) with IC50 of 0.3 uM.

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Biological Activity

Diminazene aceturate is an anti-infective agent, also is a slow pore blocker of acid-sensing ion channel 1a (ASIC1a) with IC50 of 0.3 uM.
Diminazene activates angiotensin-converting enzyme II, prevents gastric mucosal damage in mice: Role of the angiotensin-(1-7)/Mas receptor axis in mice.

Physicochemical Properties

M.Wt 515.531
Formula C22H29N9O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-4,4'-(triaz-1-ene-1,3-diyl)dibenzimidamide bis(acetylglycinate)

References

1. Schmidt A, et al. Mol Pharmacol. 2017 Dec;92(6):665-675.

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