Chemical Structure : Disitertide
CAS No.: 272105-42-7
Catalog No.: PC-47500Not For Human Use, Lab Use Only.
Disitertide (P144) is a TGF-β1 antagonist peptide, induces apoptosis in GBM cell lines and reduces SMAD2 phosphorylation with downregulation of SKI and an upregulation of SMAD7 at both transcriptional and translational levels; active in vivo.
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Disitertide (P144) is a TGF-β1 antagonist peptide, induces apoptosis in GBM cell lines and reduces SMAD2 phosphorylation with downregulation of SKI and an upregulation of SMAD7 at both transcriptional and translational levels; active in vivo.
M.Wt | 1580.824 | |
Formula | C68H109N17O22S2 | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO |
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Chemical Name/SMILES |
L-Asparagine, L-threonyl-L-seryl-L-leucyl-L-α-aspartyl-L-alanyl-L-seryl-L-isoleucyl-L-isoleucyl-L-tryptophyl-L-alanyl-L-methionyl-L-methionyl-L-glutaminyl- |
1. Gallo-Oller G, et al. Cancer Lett. 2016 Oct 10;381(1):67-75.
2. Baltanas A, et al. Antioxid Redox Signal. 2013 Nov 10;19(14):1607-18.
3. Diaz-Valdes N, et al. Cancer Res. 2011 Feb 1;71(3):812-21.
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