Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-Acetylcholinesterase (AChE)-Donepezil
Donepezil

Chemical Structure : Donepezil

CAS No.: 120014-06-4

Add to Favorites

Donepezil (E2020)

Catalog No.: PC-23391Not For Human Use, Lab Use Only.

Donepezil (E2020) is a potent, specific acetylcholinesterase (AChE) inhibitor with IC50 of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively.

Packing Price Stock Quantity
25 mg $78 In stock
100 mg $158 In stock
250 mg $248 In stock
1 g Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Donepezil (E2020) is a potent, specific acetylcholinesterase (AChE) inhibitor with IC50 of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively.
Donepezil (E2020) exerts a protective action against acute diisopropylfluorophosphate-poisoning in the mouse.

Physicochemical Properties

M.Wt 379.50
Formula C24H29NO3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one

References

1. Galli A, et al. Eur J Pharmacol. 1994 Apr 4;270(2-3):189-93.

2. Ohnishi A, et al. J Clin Pharmacol. 1993 Nov;33(11):1086-91.

3. Misson J, et al. J Clin Pharm Ther. 1997 Aug;22(4):251-5.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: