Chemical Structure : Donepezil
CAS No.: 120014-06-4
Catalog No.: PC-23391Not For Human Use, Lab Use Only.
Donepezil (E2020) is a potent, specific acetylcholinesterase (AChE) inhibitor with IC50 of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively.
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Donepezil (E2020) is a potent, specific acetylcholinesterase (AChE) inhibitor with IC50 of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively.
Donepezil (E2020) exerts a protective action against acute diisopropylfluorophosphate-poisoning in the mouse.
M.Wt | 379.50 | |
Formula | C24H29NO3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one |
1. Galli A, et al. Eur J Pharmacol. 1994 Apr 4;270(2-3):189-93.
2. Ohnishi A, et al. J Clin Pharmacol. 1993 Nov;33(11):1086-91.
3. Misson J, et al. J Clin Pharm Ther. 1997 Aug;22(4):251-5.
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