Dorzagliatin (Sinogliatin, HMS5552) | Glucokinase activator

Chemical Structure : Dorzagliatin

CAS No.: 1191995-00-2

Catalog No.: PC-35647Not For Human Use, Lab Use Only.

Dorzagliatin (Sinogliatin, HMS5552, RO 5305552) is a novel, first-in-class glucokinase activator (GKS) to treat diabetes mellitus.

Packing	Price	Stock
5 mg	$78	In stock
10 mg	$118	In stock
50 mg	$328	In stock
100 mg	$528	In stock
250 mg		Get quote

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Biological Activity

Dorzagliatin (Sinogliatin, HMS5552, RO 5305552) is a novel, first-in-class glucokinase activator (GKS) to treat diabetes mellitus.

M.Wt	462.93
Formula	C22H27ClN4O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-(4-(2-Chlorophenoxy)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(1-((R)-2,3-dihydroxypropyl)-1H-pyrazol-3-yl)-4-methylpentanamide

1. Song L, et al. Clin Pharmacokinet. 2018 Oct;57(10):1307-1323.