Doxorubicin | Topoisomerase inhibitor | Probechem Biochemicals

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Chemical Structure : Doxorubicin

CAS No.: 23214-92-8

Doxorubicin (Hydroxydaunorubicin)

Catalog No.: PC-28248Not For Human Use, Lab Use Only.

Doxorubicin (Hydroxydaunorubicin) is a cytotoxic anthracycline antibiotic with anti-cancer chemotherapy activity, is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50 of 0.8 μM and 2.67 μM, respectively.

Packing	Price	Stock
50 mg	$58	In stock
100 mg	$88	In stock
250 mg	$128	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Physicochemical Properties

M.Wt	543.53
Formula	C27H29NO11
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione

References

1. John L. Nitiss, et al. Nat Rev Cancer. 2009 May;9(5):338-50.

2. Hee-KyungRhee,et al. Bioorg Med Chem. 2007 Feb 15;15(4):1651-8.

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Doxorubicin (Hydroxydaunorubicin)

Biological Activity

Physicochemical Properties

References

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